2.6. 2 Magnesium Stearate. Magnesium stearate is the most commonly used metallic salt boundary lubricant containing two equivalents of a fatty acid (usually stearic and palmitic acid) and a charged magnesium (Zarmpi et al., 2017).
What is magnesium stearate made from?
Magnesium stearate is a simple salt made of two common nutritional substances, the mineral magnesium and the saturated fat stearic acid. It is used as a flow agent, lubricant, binder or anti-caking agent in the production of many nutritional supplements and pharmaceuticals.
Is stearate a metal?
Zinc stearate is a “zinc soap” that is widely used industrially. In this context, soap is used in its formal sense, a metal salt of a fatty acid: in this case stearic acid. It is a white solid that repels water.
What is the category of magnesium stearate?
Magnesium stearate is an additive that’s primarily used in medication capsules. It’s considered a “flow agent.” It prevents the individual ingredients in a capsule from sticking to each other and the machine that creates the capsules.
Is magnesium stearate a chemical?
It is a soap, consisting of salt containing two equivalents of stearate (the anion of stearic acid) and one magnesium cation (Mg2+). Magnesium stearate is a white, water-insoluble powder.
|Chemical formula||Mg(C 18H 35O 2) 2|
|Molar mass||591.27 g/mol|
|Appearance||light white powder|
Is magnesium stearate really bad for you?
The Health Effects of Magnesium Stearate
Magnesium stearate is generally safe to consume, but too much of it can have a laxative effect. In large amounts, it can irritate the mucus lining of the bowels. This may trigger a bowel movement or diarrhea.
Is magnesium stearate easily absorbed?
It is a very fine powder that is greasy to the touch and practically insoluble in water. Upon ingestion, magnesium stearate is dissolved into magnesium ion and stearic and palmitic acids. Magnesium is absorbed primarily in the small intestine, and to a lesser extent, in the colon.
Is magnesium stearate alkaline?
Magnesium stearate with impurities of magnesium oxide creates an alkaline environment, causing drug degradation, especially for base-sensitive molecules (Li & Wu, 2014; Nokhodchi, 2005).
How is zinc stearate made?
A preparation technology of zinc stearate comprises the following steps that 1, glyceryl tristearate and water are hydrolyzed under the action of a catalyst and an antioxidant; 2, zinc oxide and a catalyst are added stepwise, condensing, dewatering and salt forming are conducted, and zinc stearate is synthesized.
Is zinc stearate the same as zinc oxide?
In cosmetics, zinc stearate is a lubricant and thickening to improve texture. The insoluble salt is made of commercial stearic acid, a type of mild fatty acid that is used as an emollient and lubricant. It is often combined with zinc oxide. Zinc, on its own, is known to have antibacterial and antiviral properties.
Is magnesium a metal?
A silvery-white metal that ignites easily in air and burns with a bright light. Magnesium is one-third less dense than aluminium.
Is magnesium stearate flammable?
Under Fire Conditions: Not flammable. In common with many organic chemicals in powder form, this product may be capable of forming flammable dust clouds in air. Hazardous Polymerization: Will not occur. Conditions to Avoid: High temperatures, sparks, open flames and all other sources of ignition.
Is magnesium stearate natural or synthetic?
#2: Magnesium Stearate is a synthetic additive and due to this fact, the body does not have a natural mechanism in place for utilizing it.
Is magnesium stearate safe for the liver?
Is it safe? Magnesium stearate is not to be taken in large amounts because, in large amounts, it causes liver toxicity and skin irritation.
Why is magnesium stearate used as a lubricant?
Magnesium stearate, a metallic salt boundary lubricant, is probably the most commonly used lubricant for pharmaceutical tableting; it is relatively inexpensive, provides high lubrication, has a high melting point, and is chemically stable (2).
What is plant-based magnesium stearate?
Vegetable magnesium stearate is mostly made from palm oil and is a standard for tablets. However, it can also be derived from purified cottonseed oil. Magnesium Stearate in supplement tablets is used as a ‘flow agent’.
Is magnesium stearate pork?
Another filler you’ll often see listed in the ingredient list is magnesium stearate, which is normally pork-derived. … Magnesium stearate comes from stearic acid, which is a fatty acid usually found in pork, butter, chicken, beef, fish, and milk. It’s also found in cocoa and grains.
Can vegans get magnesium stearate?
Magnesium Stearate is generally vegan but may possibly be derived from or processed with non-vegan sources.
Is magnesium stearate vegan friendly?
Classification: Vegan* Although it is possible to derive magnesium stearate from animal fats, it is not standard practice today in the food industry and no examples of tallow-derived magnesium stearate in foods or pharmaceuticals are known.
Is magnesium stearate dairy free?
Magnesium Stearate is dairy free. Magnesium Stearate does not contain milk and should be safe for those with a milk allergy.
Is magnesium stearate halal?
The ingredients magnesium stearate and glycerin are considered Halal if it originated from a plant source and Haram if originated from an animal source.
Does magnesium stearate contain alpha gal?
Alpha-gal has not been definitively found in magnesium stearate, as this study has yet to be conducted. The correlation is theoretical.
Is alpha-gal syndrome an autoimmune disease?
The allergy component of AGS is only one dimension of a complex immune response that may have other health implications (7). Conditions tentatively linked to the alpha-gal immune response include some autoimmune diseases (7), arthritis (60), and atherosclerosis (79,80).
Are there any side effects from magnesium Glycinate?
Taking large or frequent doses of dietary magnesium supplements, including magnesium glycinate, can cause adverse effects, including diarrhea, nausea, and stomach cramps. Extremely high intakes of magnesium can lead to an irregular heartbeat and potentially a cardiac arrest, which can be dangerous.
Does alpha-gal go away?
Alpha-gal syndrome doesn’t go away, but you can manage symptoms by avoiding: Meats, organs, and blood of mammals.
Does bacon contain alpha-gal?
Because Alpha-Gal is also found in red meat, a bite by the Lone Star tick may translate to an allergic reaction to anything from beef hamburgers to bacon. Repeated tick bites can potentially cause the antibody level of Alpha-Gal to rise, worsening reactions.
How do I know if I have alpha-gal?
Signs and symptoms of alpha-gal syndrome may include:
- Hives, itching, or itchy, scaly skin (eczema)
- Swelling of the lips, face, tongue and throat, or other body parts.
- Wheezing or shortness of breath.
- A runny nose.
- Stomach pain, diarrhea, nausea or vomiting.